Key result
High-intensity intermittent exercise and moderate-intensity exercise yielded similar 24-hour CGM time in range (79.5% vs 76.1%, P=0.37) in adults with type 1 diabetes.
Why the study?
To evaluate exercise-related glucose and counterregulatory responses in adults with type 1 diabetes and impaired awareness of hypoglycemia using hybrid closed-loop insulin delivery.
Does high-intensity intermittent exercise compared to moderate-intensity exercise affect continuous glucose monitoring time in range in adults with type 1 diabetes and impaired awareness of hypoglycemia using closed-loop insulin delivery?
Comparison
45-min high-intensity intermittent exercise vs moderate-intensity exercise
Design
Randomized crossover study
Follow-up
24-h post-exercise commencement
Authors
Loading...
Either exercise intensity may suit glycemic management in T1D; hypothesis-generating, larger trials needed.
RCT (n=12)
Random order
Does high-intensity intermittent exercise compared to moderate-intensity exercise affect continuous glucose monitoring time in range in adults with type 1 diabetes and impaired awareness of hypoglycemia using closed-loop insulin delivery?
Absolute Event Rate: 79.5% vs 76.1%
p-value: p=0.37
In adults with type 1 diabetes and impaired awareness of hypoglycemia using hybrid closed-loop insulin delivery, high-intensity intermittent exercise and moderate-intensity exercise resulted in similar 24-hour time in range without severe hypoglycemia.
Lee et al. (2019) conducted an RCT in Type 1 diabetes with impaired awareness of hypoglycemia (n=12). High-intensity intermittent exercise (HIIE) vs. Moderate-intensity exercise (MIE) was evaluated on Continuous glucose monitoring (CGM) time in range (70–180 mg/dL) for 24-h post-exercise commencement (p=0.37). High-intensity intermittent exercise and moderate-intensity exercise yielded similar 24-hour CGM time in range (79.5% vs 76.1%, P=0.37) in adults with type 1 diabetes.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: