Why the study?
Does an age-adjusted warfarin initiation protocol improve the time to reach a stable INR in patients commencing warfarin therapy?
Population
73 inpatients and outpatients commencing warfarin therapy
Design
Cohort
Follow-up
6 days
Authors
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Age-adjusted warfarin titration may achieve stable INR in most by day 6; hypothesis-generating and should not yet change practice pending RCTs.
Does an age-adjusted warfarin initiation protocol improve the time to reach a stable INR in patients commencing warfarin therapy?
An age-adjusted warfarin initiation protocol rapidly achieves a stable INR with minimal overanticoagulation.
Roberts et al. (2003) studied this question.
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