Why the study?
Does propranolol alter the hemodynamic response to supine exercise in normal subjects?
Population
6 normal subjects
Comparison
Beta-adrenergic blockade with propranolol vs Baseline (before blockade)
Design
Other
Authors
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Blunts exercise hemodynamics in healthy subjects without limiting capacity; extends foundational physiology but leaves open effects in cardiovascular disease.
Does propranolol alter the hemodynamic response to supine exercise in normal subjects?
Beta-adrenergic blockade with propranolol significantly reduces resting and exercise heart rate and cardiac output in normal subjects without impairing the ability to complete chosen exercise loads.
Cumming et al. (1966) studied this question.
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