Why the study?
Does propranolol alter left ventricular function during rest and exercise in normal young men?
Population
12 normal young male volunteers, ages 21-29 years
Comparison
Propranolol 320 mg/day orally for 2 days vs Control measurements taken at least 48 hours…
Design
Other
Follow-up
2 days of treatment, followed by >48 hours washout
Authors
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Propranolol may impair exercise hemodynamics in healthy subjects; leaves open differential effects in cardiovascular disease.
Does propranolol alter left ventricular function during rest and exercise in normal young men?
Propranolol alters rest and exercise hemodynamics in healthy adults primarily through alterations in heart rate.
Port et al. (1980) studied this question.