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February 1, 1993Radiology

Carotid artery: prospective blinded comparison of two-dimensional time-of-flight MR angiography with conventional angiography and duplex US.

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Why the study?

Does 2D time-of-flight MR angiography and color duplex flow ultrasound accurately characterize the degree of carotid stenosis compared to conventional angiography in patients with hemispheric ischemic symptoms?

Population

50 patients with hemispheric ischemic symptoms

Comparison

Two-dimensional time-of-flight magnetic… vs Conventional angiography

Design

Cross-sectional, blinded

Authors

JHJohn HustonCardiac ImagingBLBradley LewisMayo ClinicDWDavid O. WiebersMayo Clinic

Discussion

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Implication

Supports 2D TF MIP matching duplex US for carotid stenosis assessment; leaves open accuracy versus conventional angiography in symptomatic patients.

Structured PICO

Does 2D time-of-flight MR angiography and color duplex flow ultrasound accurately characterize the degree of carotid stenosis compared to conventional angiography in patients with hemispheric ischemic symptoms?

P
Population
50 patients with hemispheric ischemic symptoms
I
Intervention
Two-dimensional (2D) time-of-flight (TF) magnetic resonance (MR) angiography and color duplex flow ultrasound (US)
C
Comparator
Conventional angiography (as a standard of reference)
O
Outcome
Accuracy in characterizing the degree of carotid stenosis (measured by means of receiver operating characteristic curves)surrogate

2D time-of-flight MR angiography matches the accuracy of duplex ultrasound for evaluating carotid stenosis but overrepresents stenosis degree and cannot replace conventional angiography.

Cite This Study

Huston et al. (1993) studied this question.

synapsesocial.com/papers/6a70f15535aa2c282ce244bfhttps://doi.org/10.1148/radiology.186.2.8421731
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Detection of internal carotid artery stenosis: comparison of MR angiography, color Doppler sonography, and arteriography.1992 · 150 citations
  2. 2Comparison of Ultrasonography and Magnetic Resonance Angiography in Patients with Carotid Artery Disease.1998
  3. 3Carotid artery stenosis: clinical efficacy of two-dimensional time-of-flight MR angiography.1992 · 133 citations
  4. 4Carotid Arteries: Contrast-enhanced US Angiography—Preliminary Clinical Experience2004 · 106 citations
  5. 5Comparison of intra-arterial digital subtraction angiography, magnetic resonance angiography and duplex ultrasonography for measuring carotid artery stenosis1999 · 46 citations