February 1, 2004Radiology
Carotid Arteries: Contrast-enhanced US Angiography—Preliminary Clinical Experience
Why the study?
Does contrast-enhanced US angiography accurately depict carotid artery stenosis compared to conventional angiography in patients with carotid artery disease?
Population
Human subjects with carotid artery disease
Comparison
B-mode ultrasonographic angiography enhanced… vs Duplex US and conventional angiography
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May support noninvasive carotid stenosis assessment; leaves open prospective outcome trials before clinical adoption.
Structured PICO
Does contrast-enhanced US angiography accurately depict carotid artery stenosis compared to conventional angiography in patients with carotid artery disease?
P
Population
Human subjects with carotid artery disease
I
Intervention
B-mode ultrasonographic (US) angiography enhanced with a microbubble-based US contrast agent (FS069)
C
Comparator
Duplex US and conventional angiography
O
Outcome
Accuracy in depicting stenoses of 70% or more and correlation of percentage diameter stenosissurrogate
Contrast-enhanced US angiography with FS069 accurately depicts severe carotid stenosis and correlates strongly with conventional angiography.
Cite This Study
Kono et al. (2004) studied this question.