Why the study?
Does intracerebroventricular infusion of moxonidine improve survival in a rat model of hypertensive heart failure?
Does intracerebroventricular infusion of moxonidine improve survival in a rat model of hypertensive heart failure?
Central sympathoinhibition with moxonidine improved survival and attenuated cardiac dysfunction and remodeling in a rat model of hypertensive heart failure.
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Survival benefit in rat hypertensive HF; leaves open clinical translation of central sympathoinhibition.
Honda et al. (2013) studied this question.
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