Why the study?
High BMI may affect outcomes after cardiac arrest, but its association with outcomes in patients with ROSC after OHCA remains debatable.
Does abnormal BMI (underweight or obese) worsen neurological outcomes and in-hospital mortality in patients with ROSC after OHCA compared to normal weight?
Population
2427 patients from six studies with ROSC after OHCA and recorded BMI
Comparison
Underweight and obese patients vs normal-weight patients
Design
Systematic review and meta-analysis of non-randomized studies
Authors
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No independent BMI-outcome link after adjustment; leaves open BMI's prognostic role in ROSC-OHCA survivors.
Does abnormal BMI (underweight or obese) worsen neurological outcomes and in-hospital mortality in patients with ROSC after OHCA compared to normal weight?
Both underweight and obesity are associated with increased in-hospital mortality in patients achieving ROSC after OHCA, with underweight also linked to poorer neurological outcomes.
Lee et al. (2021) studied this question.
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