Why the study?
Does peroxynitrite administration at reperfusion aggravate myocardial injury in isolated perfused rat hearts?
Does peroxynitrite administration at reperfusion aggravate myocardial injury in isolated perfused rat hearts?
Peroxynitrite plays a significant detrimental role in postischemic myocardial injury, and its detoxification or prevention of formation exerts cardioprotective effects in a rat model.
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Peroxynitrite donor impairs postischemic recovery in isolated rat hearts; hypothesis-generating for peroxynitrite inhibition in clinical reperfusion injury.
X Ma (1997) studied this question.
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