Why the study?
Does mitral valve replacement improve hemodynamics and survival in patients with severe pulmonary arterial hypertension?
Population
43 patients with severe pulmonary arterial hypertension undergoing mitral valve replacement, mean age 30.6…
Design
Cohort
Follow-up
immediate postoperative
Authors
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Supra-systemic pressures signal high operative risk after mitral valve replacement; this cohort finding leaves open whether preoperative pressure reduction improves survival.
Does mitral valve replacement improve hemodynamics and survival in patients with severe pulmonary arterial hypertension?
Mitral valve replacement is relatively safe in severe pulmonary arterial hypertension if pulmonary arterial pressures are sub-systemic, but carries high operative mortality when pressures are supra-systemic.
Mubeen et al. (2008) studied this question.
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