Population
Tissues from 3 human subjects obtained at autopsy
Comparison
Quantitative polymerase chain reaction technique… vs Cardiac ventricular tissues vs extracardiac…
Design
Preclinical
Authors
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Hypothesis-generating for extracardiac natriuretic peptide functions; human studies required before any clinical consideration.
Demonstrates the local synthesis of ANP and BNP in various human peripheral organs, suggesting potential paracrine and/or autocrine functions.
Gerbes et al. (1994) studied this question.
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