Why the study?
Does AV sequential pacing improve left ventricular relaxation compared to VVI pacing in dogs with complete heart block?
Does AV sequential pacing improve left ventricular relaxation compared to VVI pacing in dogs with complete heart block?
In a canine model of complete heart block, AV sequential pacing increases stroke volume and cardiac output compared to VVI pacing but does not improve left ventricular relaxation, likely due to nonuniform ventricular activation.
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AV sequential pacing boosts output without improving relaxation in canine heart block; leaves open activation sequence effects on diastolic function.
Litwin et al. (1989) studied this question.
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