Population
Anaesthetized rats
Comparison
Bilateral microinjections of… vs Control rats
Design
Preclinical
Authors
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Challenges necessity of C1 cells for basal tone in rats; leaves open their contribution to human sympathetic regulation.
C1 cells in the rostral ventrolateral medulla are critical for the full expression of sympathoexcitatory responses but are not required for maintaining resting sympathetic tone and arterial pressure.
Schreihofer et al. (2000) studied this question.
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