Population
Conscious spontaneous hypertensive rats, normotensive Wistar-Kyoto rats, Dahl salt-sensitive rats, and…
Comparison
Intravenous isotonic saline volume expansion… vs Normotensive Wistar-Kyoto rats for SHR; low vs…
Design
Preclinical
Authors
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Does not inform clinical renal denervation use; extends baroreflex-natriuresis mechanisms in experimental hypertension models.
Enhanced inhibition of efferent renal sympathetic nerve activity via cardiopulmonary baroreceptor reflex activation contributes to the exaggerated natriuretic response to volume expansion in specific experimental hypertension models.
DiBona et al. (1986) studied this question.
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