Why the study?
Are prediagnostic serum concentrations of C-peptide, IGFBP-1, and IGFBP-2 associated with incident endometrial cancer risk in women?
Are prediagnostic serum concentrations of C-peptide, IGFBP-1, and IGFBP-2 associated with incident endometrial cancer risk in women?
Elevated C-peptide levels may be marginally associated with an increased risk of endometrial cancer, providing modest support for hyperinsulinemia as a risk factor.
Authors
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Marginal C-peptide link should not alter clinical risk assessment; leaves open hyperinsulinemia's role pending prospective validation.
Cust et al. (2007) studied this question.
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