Why the study?
Does prehypertension or hypertension impair coronary flow reserve compared to normotensive individuals?
Population
150 subjects without systemic disease, comprising 40 with prehypertension, 60 with hypertension, and 50…
Comparison
Prehypertension and hypertension vs Normotensive healthy volunteers
Design
Cross-sectional
Authors
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Prehypertension and hypertension were associated with lower CFR; extends microvascular observations but remains hypothesis-generating.
Does prehypertension or hypertension impair coronary flow reserve compared to normotensive individuals?
Prehypertension is associated with impaired coronary microvascular function, though less severe than in established hypertension, suggesting early microvascular changes.
Erdoğan et al. (2007) studied this question.
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