Key result
Reduced coronary flow reserve in newly diagnosed hypertensive patients is significantly associated with impaired left ventricular relaxation and increased filling pressure, independent of LV geometry.
Why the study?
Is impaired coronary flow reserve associated with left ventricular systolic and diastolic dysfunction independent of left ventricular geometry in newly diagnosed hypertensive patients?
Cross-Sectional (n=59)
Is impaired coronary flow reserve associated with left ventricular systolic and diastolic dysfunction independent of left ventricular geometry in newly diagnosed hypertensive patients?
In newly diagnosed hypertensive patients, reduced coronary flow reserve is independently associated with impaired left ventricular relaxation and increased filling pressure, regardless of left ventricular geometry.
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May support CFR as LV function marker in hypertension; leaves open diagnostic utility and outcome impact.
Galderisi et al. (2008) conducted a cross-sectional in Arterial hypertension (n=59). Reduced coronary flow reserve (CFR) was evaluated on Left ventricular systolic and diastolic function parameters (midwall shortening, IVRT, Em, E/Em ratio). Reduced coronary flow reserve in newly diagnosed hypertensive patients is significantly associated with impaired left ventricular relaxation and increased filling pressure, independent of LV geometry.
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