June 1, 2016Journal of EndocrinologyOpen Access

Obesity, hypertension and aldosterone: is leptin the link?

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Population

Obese individuals with hypertension

Design

Review

Authors

DXDing XieAugusta University WBWendy B. BollagAugusta University

Discussion

Member takes

Implication

Excess body weight drives most hypertension risk; supports weight management focus but leaves open causal trials.

Structured PICO

Population

Obese individuals with hypertension

Adipose-released factors such as leptin and VLDL may directly stimulate aldosterone biosynthesis, offering a mechanistic explanation for obesity-induced hypertension.

Cite This Study

Xie et al. (2016) studied this question.

synapsesocial.com/papers/6a710caaaf0c21e93928bdbd https://doi.org/10.1530/joe-16-0160

Topics

Hypertension management

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Obesity, hypertension and aldosterone: is leptin the link?

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Obesity, hypertension and aldosterone: is leptin the link?

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider