Vascular and organoprotective properties of fixed combination of perindopril/indapamid in hypertensive patients

56 patients with arterial hypertension of the 1-2 degrees (AH 1-2) aged 50.6 ± 0.6 years old, and 25 healthy volunteers.

Fixed low- and full-dose combination of perindopril/indapamide administered for a period of 12 months.

Office blood pressure, endothelial function, aorta and large arteries stiffness, indices reflecting remodeling of the heart, renal and cerebral blood vessels, microalbuminuria and glomerular filtration rate at 12 months.surrogate