Why the study?
Does perindopril/indapamide combination therapy improve blood pressure control and reduce target organ damage in patients with hypertension?
Population
Patients with hypertension, including those at high cardiovascular risk such as patients with cardiac…
Comparison
Perindopril 2 mg/indapamide 0.625 mg once-daily… vs Other first-line therapies, current…
Design
Review
Authors
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May support perindopril/indapamide in hypertension; leaves open confirmation in prospective outcome trials.
Does perindopril/indapamide combination therapy improve blood pressure control and reduce target organ damage in patients with hypertension?
Perindopril/indapamide is an effective and well-tolerated first-line combination therapy for hypertension that provides additional blood pressure lowering and end-organ protection compared to monotherapies.
Philippe Gosse (2006) studied this question.
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