Why the study?
Does delapril or TCV-116 improve hemodynamic and metabolic profiles in spontaneously hypertensive rats?
Does delapril or TCV-116 improve hemodynamic and metabolic profiles in spontaneously hypertensive rats?
In spontaneously hypertensive rats, oral delapril exhibits more complex depressor properties than TCV-116, while central blockade by both agents decreases blood pressure partly through baroreceptor sensitization.
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These rat findings highlight delapril's distinct effects; leaves open any human translation or clinical differentiation.
Kohara et al. (1993) studied this question.
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