Influence of acute alcohol exposure on hemorheological parameters and platelet function in vivo and in vitro

12 healthy male volunteers

4.36 ml red wine/kg body weight (=0.5 g ethanol/kg) ingested at 06.00 p.m. under fasting conditions (in vivo), and 0-100 mmol/l ethanol incubation for 1 h at 37 degrees C (in vitro)

Water (in vivo)

Blood flow properties (hemorheological parameters including mean cellular volume and whole blood viscosity) and platelet function (aggregation)surrogate