April 1, 2000Alcoholism Clinical and Experimental Research

Effects of Acute, Moderate Ethanol Consumption on Human Platelet Aggregation in Platelet‐Rich Plasma and Whole Blood

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Why the study?

Does acute moderate ethanol consumption reduce platelet aggregation in healthy human subjects?

Population

Healthy human subjects (male and female)

Design

Other

Follow-up

1 hour

Authors

QZQinghui ZhangShanghai Jiao Tong University KDKabita DasGeorgetown University SSShahid SiddiquiUniversity of Hertfordshire

Discussion

Member takes

Implication

Acute moderate ethanol may inhibit platelet aggregation in healthy subjects; hypothesis-generating for any CAD protection.

Structured PICO

Does acute moderate ethanol consumption reduce platelet aggregation in healthy human subjects?

Population

Healthy human subjects (male and female)

Intervention

Acute consumption of ethanol at a dose equivalent to one drink (0.25 ml/kg) or two drinks (0.5 ml/kg)

Outcome

Agonist-induced aggregation of platelets measured in whole blood and platelet-rich plasma 1 hour after ingestionsurrogate

Acute moderate ethanol consumption dose-dependently inhibits platelet aggregation, which may contribute to its protective effects against coronary artery disease.

Cite This Study

Zhang et al. (2000) studied this question.

synapsesocial.com/papers/6a8968eb5edafe343d92dbb1 https://doi.org/10.1111/j.1530-0277.2000.tb02021.x

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Effects of Acute, Moderate Ethanol Consumption on Human Platelet Aggregation in Platelet‐Rich Plasma and Whole Blood

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Effects of Acute, Moderate Ethanol Consumption on Human Platelet Aggregation in Platelet‐Rich Plasma and Whole Blood

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider