Why the study?
Does inactivated poliovirus vaccine (IPV) compared to oral live poliovirus vaccine (OPV) improve secretory IgA antibody responses in milk and saliva?
Population
Individuals (likely lactating women) receiving poliovirus vaccination
Comparison
Inactivated poliovirus vaccine (IPV) vs Oral, live poliovirus vaccine (OPV)
Design
Other
Authors
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IPV may boost milk IgA more than OPV in lactating women; leaves open effects on infant protection and vaccination policy.
Does inactivated poliovirus vaccine (IPV) compared to oral live poliovirus vaccine (OPV) improve secretory IgA antibody responses in milk and saliva?
Inactivated poliovirus vaccine is more effective than oral live vaccine at increasing secretory IgA antibody titers in milk.
Hanson et al. (1984) studied this question.
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