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January 1, 2011Chemotherapy

Clinical and Electrocardiography Changes in Patients Treated with Capecitabine

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Why the study?

What is the incidence of cardiac events in cancer patients treated with capecitabine?

Population

52 patients with cancer, median age 59 years, treated at a Medical Oncology Clinic between 2009 and 2010.

Design

Cohort

Authors

DKDoğan KocaSağlık Bilimleri ÜniversitesiTSTarık SalmanIzmir UniversityİÜİlkay Tuğba ÜnekDokuz Eylül University

Discussion

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Implication

May support vigilant cardiac monitoring with capecitabine; leaves open optimal surveillance strategies.

Structured PICO

What is the incidence of cardiac events in cancer patients treated with capecitabine?

P
Population
52 patients with cancer, median age 59 years, treated at a Medical Oncology Clinic between 2009 and 2010.
I
Intervention
Capecitabine treatment (either single-agent or combination chemotherapy)
O
Outcome
Incidence of cardiac events (classified into cardiac symptoms, physical signs, electrocardiography findings, and severe adverse cardiac effects)safety

Capecitabine treatment is associated with a high incidence of cardiac events, including ECG changes and symptoms, warranting close cardiovascular monitoring.

Cite This Study

Koca et al. (2011) studied this question.

synapsesocial.com/papers/6a711cd3660549caf2c5beebhttps://doi.org/10.1159/000331645

Topics

Women and heart disease
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