Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 1, 2010Journal of Clinical Medicine ResearchOpen Access

Aortic Stiffness in Prediabetic Adults: Relationship to Insulin Resistance

View Full Paper
Ask AI
Bookmark
Share

Population

158 adults, comprising 113 consecutive adults with prediabetes and 45 healthy age- and gender-matched…

Design

Case-control

Authors

HSHamdy SliemSuez Canal University

Discussion

Loading...

Member takes

Implication

May inform early vascular risk assessment in prediabetes; leaves open causal role of insulin resistance pending prospective studies.

Structured PICO

P
Population
158 adults, comprising 113 consecutive adults with prediabetes (32 with insulin resistance, 81 insulin sensitive) and 45 healthy age- and gender-matched controls.
O
Outcome
Aortic stiffness index assessed by echocardiographysurrogate

Insulin resistance is associated with increased aortic stiffness in prediabetic adults independent of glucose levels and obesity, highlighting a mechanism for early cardiovascular risk.

Cite This Study

Hamdy Sliem (2010) studied this question.

synapsesocial.com/papers/6a71236d87f9210571281210https://doi.org/10.4021/jocmr2010.03.269w
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Aortic Stiffness Is Associated With Visceral Adiposity in Older Adults Enrolled in the Study of Health, Aging, and Body Composition2001 · 390 citations
  2. 2Aortic Stiffness Is an Independent Predictor of All-Cause and Cardiovascular Mortality in Hypertensive Patients2001 · 3,873 citations
  3. 3Left Ventricular Structural and Functional Changes in the Metabolic Syndrome2009 · 15 citations
  4. 4An Adipocyte-Derived Plasma Protein, Adiponectin, Adheres to Injured Vascular Walls2000 · 568 citations
  5. 5Clustering of metabolic syndrome risk factors and arterial stiffness in young adults: the Northern Ireland Young Hearts Project2007 · 93 citations