January 1, 2002Seminars in Vascular Medicine
Arterial Stiffness and Insulin Resistance
Key result
Insulin resistance blunts the normal ability of insulin to acutely diminish arterial stiffness, providing a potential mechanistic link between insulin resistance and systolic hypertension.
Design
Review
Authors
Discussion
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Overview
Does not yet support practice change; hypothesis-generating for arterial stiffness as a therapeutic target in insulin-resistant hypertension.
PICO
P
Population
Insulin resistance and arterial stiffness
E
Exposure / Comparator
Insulin resistance vs Normal insulin sensitivity
The inability of insulin to normally diminish arterial stiffness may provide a mechanistic link between insulin resistance and systolic hypertension.
Cite This Study
Westerbacka et al. (2002) conducted a review in Insulin resistance and arterial stiffness. Insulin resistance vs. Normal insulin sensitivity was evaluated. Insulin resistance blunts the normal ability of insulin to acutely diminish arterial stiffness, providing a potential mechanistic link between insulin resistance and systolic hypertension.