Population
Framingham Heart Study families, evaluated over three age groups (31-49 years, 50-60 years, and 61-79 years)
Design
Cohort
Authors
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Heritability of BP and BMI varies with age; hypothesis-generating for shared genetic effects on longitudinal CV risk and needs prospective confirmation.
Heritability of cardiovascular risk factors such as BMI and systolic blood pressure shows some variation by age but suggests a common set of genes contributes to longitudinal variation.
Brown et al. (2003) studied this question.
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