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Challenges traditional peripheral fatigue models; leaves open prospective validation before guiding training or rehab protocols.
Fatigue is hypothesised as being the result of the complex interaction of multiple peripheral physiological systems and the brain. In this new model, all changes in peripheral physiological systems such as substrate depletion or metabolite accumulation act as afferent signallers which modulate control processes in the brain in a dynamic, non-linear, integrative manner.
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Lambert et al. (2004) studied this question.
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