Morning Blood Pressure Surge: The Reliability of Different Definitions
Why the study?
Which definition of morning blood pressure surge provides the highest reproducibility in untreated hypertensive patients?
Population
132 untreated hypertensives
Design
Cohort
Follow-up
2 weeks
Authors
Discussion
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Member takes
Implication
MS4 may aid reproducible surge assessment in research; leaves open outcome prediction and should not yet change practice.
Structured PICO
Which definition of morning blood pressure surge provides the highest reproducibility in untreated hypertensive patients?
P
Population
132 untreated hypertensives
I
Intervention
Five different definitions of morning blood pressure surge (MS-1 to MS-5) assessed via ambulatory BP monitoring twice, 2 weeks apart
O
Outcome
Reproducibility of each MS definition assessed using concordance correlation coefficient (CCC), standard deviation of differences (SDD), coefficient of variation (CV), and agreement in detecting 'surgers'surrogate
Defining morning blood pressure surge as the BP 2 hours after rising minus the average BP during sleep provides the most reproducible measurement for clinical assessment.
Cite This Study
Stergiou et al. (2008) studied this question.