Why the study?
What is the relative importance of ionic properties, specifically the Na+/K+ pump, in modulating excitability, refractoriness, and rotor dynamics in human atria before and after AF-related electrical remodeling?
Population
Computer simulations of single cell and tissue atrial electrophysiology using two human atrial action…
Comparison
Alterations in key properties of atrial ionic… vs Before and after AF-related electrical remodeling
Design
Preclinical
Authors
Loading...
Computer simulations demonstrate that the Na+/K+ pump current is a critical modulator of human atrial electrophysiology and rotor dynamics, suggesting its importance in atrial fibrillation mechanisms.
What is the relative importance of ionic properties, specifically the Na+/K+ pump, in modulating excitability, refractoriness, and rotor dynamics in human atria before and after AF-related electrical remodeling?
Computer simulations demonstrate that the Na+/K+ pump current is a critical modulator of human atrial electrophysiology and rotor dynamics, suggesting its importance in atrial fibrillation mechanisms.
Sánchez et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: