Population
18 isolated Langendorff-perfused rabbit hearts
Design
Preclinical
Authors
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Rate correction of repolarization dispersion may be unnecessary; leaves open human translation from this isolated rabbit model.
In an isolated rabbit heart model, dispersion of ventricular repolarization does not change significantly with heart rate, suggesting that rate correction of dispersion parameters may be unnecessary.
Zabel et al. (1997) studied this question.
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