Why the study?
Does ACE gene I/D polymorphism affect the antiproteinuric response to ACE inhibitors in patients with proteinuria?
Population
36 patients with proteinuria (23 men and 13 women; mean age, 47 +/- 13 years)
Comparison
ACE inhibitors in patients with ACE gene I/D… vs ACE inhibitors in patients with genotype II
Design
Cohort
Authors
Loading...
ACE I/D polymorphism was associated with variable ACE inhibitor response in proteinuria; leaves open whether genotyping should guide therapy pending prospective trials.
Does ACE gene I/D polymorphism affect the antiproteinuric response to ACE inhibitors in patients with proteinuria?
The ACE gene I/D polymorphism is significantly associated with the antiproteinuric efficacy of ACE inhibitors in patients with proteinuria.
Moriyama et al. (1995) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: