Population
Actin monomers
Comparison
Various conditions including binding DNase I… vs Native/baseline state
Design
Preclinical
Authors
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Actin rigidity under physiological conditions may inform cardiac cytoskeletal models; leaves open any clinical translation or therapeutic relevance.
The region involving Tyr-69 and Cys-374 in actin is substantially rigid during physiological interactions but undergoes significant conformational changes during denaturation.
Masao Miki (1991) studied this question.
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