Population
Rabbit skeletal muscle F-actin and chicken gizzard heavy meromyosin in which heavy chains were cleaved with…
Comparison
Chemical cross-linking with… vs EDC treatment of HMM in the absence of F-actin
Design
Preclinical
Authors
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No immediate clinical implications; leaves open whether myosin head associations modulate human vascular smooth muscle function.
The study provides biochemical evidence for the association between two myosin heads in rigor acto-smooth muscle heavy meromyosin through the identification of a 60K cross-linked dimer.
Onishi et al. (1989) studied this question.
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