Population
Heavy meromyosin and subfragment 1 preparations obtained by papain digestion of myosin in the presence of…
Design
Preclinical
Authors
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Hypothesis-generating for myosin temperature sensitivity in muscle; leaves open translation to cardiac force generation.
Demonstrates a temperature-dependent conformational transition in the myosin head-rod junction that may contribute to the temperature sensitivity of force generation in muscle.
Rędowicz et al. (1988) studied this question.
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