June 1, 2005The Pediatric Infectious Disease Journal

Diagnosis and Outcomes of Enterovirus Infections in Young Infants

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Why the study?

Does PCR testing of blood and CSF improve the diagnosis of enterovirus infections in febrile infants younger than 90 days?

Population

1,779 febrile infants younger than 90 days of age evaluated for sepsis at a single center in Salt Lake City…

Design

Cohort

Authors

KRKristine R. RittichierUniversity of Utah PBPaul A. BryanUniversity of Utah KBKathlene E. BassettUniversity of Utah

Discussion

Member takes

Implication

May improve enterovirus detection in febrile infants via dual blood-CSF PCR; leaves open effects on management.

Structured PICO

Does PCR testing of blood and CSF improve the diagnosis of enterovirus infections in febrile infants younger than 90 days?

Population

1,779 febrile infants younger than 90 days of age evaluated for sepsis at a single center in Salt Lake City, UT, of whom 1,061 had enterovirus testing and 214 were positive.

Intervention

Polymerase chain reaction (PCR) testing of blood and cerebrospinal fluid (CSF) for enterovirus.

Outcome

Diagnostic yield of enterovirus PCR in blood versus CSF.surrogate

Testing both blood and CSF by PCR improves the diagnostic yield for enterovirus in young febrile infants compared to testing either specimen alone.

Cite This Study

Rittichier et al. (2005) studied this question.

synapsesocial.com/papers/6a7146baac440176ef29f3c2 https://doi.org/10.1097/01.inf.0000164810.60080.ad

View Full Paper

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Diagnosis and Outcomes of Enterovirus Infections in Young Infants

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Diagnosis and Outcomes of Enterovirus Infections in Young Infants

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider