July 1, 2003Clinical Infectious Diseases

Diagnosis of Enterovirus Infection in the First 2 Months of Life by Real-Time Polymerase Chain Reaction

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Why the study?

Does real-time PCR effectively detect enterovirus infection in infants ≤60 days old with clinical sepsis?

Structured PICO

Does real-time PCR effectively detect enterovirus infection in infants ≤60 days old with clinical sepsis?

Population

45 infants ≤60 days old who had received a clinical diagnosis of sepsis (19 admitted to pediatric wards of 2 general hospitals, 26 hospitalized since birth in the neonatal intensive care unit of a tertiary care hospital)

Intervention

Real-time polymerase chain reaction (PCR) in blood, feces, and cerebrospinal fluid samples

Outcome

Incidence of enterovirus infections

Real-time PCR in serum is a rapid and sensitive method for diagnosing enterovirus infection, which is a significant cause of sepsis in young infants admitted to the hospital.

Discussion

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Implication

Supports considering real-time PCR for enterovirus in non-NICU infant sepsis; leaves open impact on outcomes and NICU protocols.

Cite This Study

Verboon-Maciolek et al. (2003) studied this question.

synapsesocial.com/papers/6a71001c2163a0a01bc53103 https://doi.org/10.1086/375222

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Ask AI

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Diagnosis of Enterovirus Infection in the First 2 Months of Life by Real-Time Polymerase Chain Reaction

Structured PICO

Discussion

Implication

Cite This Study

Diagnosis of Enterovirus Infection in the First 2 Months of Life by Real-Time Polymerase Chain Reaction

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider