Population
Isolated soleus muscles from young (2.5-8 months old, n=12) and aged (28-31 months old, n=9) mice
Comparison
Isovelocity stretching and shortening contractions vs Muscles from young mice
Design
Preclinical
Authors
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Age-related isometric weakness absent during rapid stretch in mice; leaves open translation to human sarcopenia or clinical relevance.
In isolated mouse soleus muscles, age-related weakness observed during isometric and shortening contractions is absent during rapid stretching.
Phillips et al. (1991) studied this question.
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