Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 4, 2019Journal of Receptors and Signal TransductionOpen Access

The Angiopoietin ligands and Tie receptors: potential diagnostic biomarkers of vascular disease

View Full Paper
Ask AI
Bookmark
Share

Why the study?

The Angiopoietin/Tie pathway regulates endothelial integrity and vascular stability, prompting an evaluation of these molecules as potential clinical biomarkers in vascular complications.

Design

Review

Authors

JBJay BilimoriaDe Montfort UniversityHSHarprit SinghDe Montfort University

Discussion

Loading...

Member takes

Implication

Angpt1/Tie2 signaling may regulate vascular leakage; leaves open whether pathway modulators improve clinical outcomes.

Key Points

Key points are not available for this paper at this time.

Cite This Study

Bilimoria et al. (2019) studied this question.

synapsesocial.com/papers/6a7148ad3ce530166bc30e40https://doi.org/10.1080/10799893.2019.1652650
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Tie1 controls angiopoietin function in vascular remodeling and inflammation2016 · 307 citations
  2. 2Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice2015 · 57 citations
  3. 3Protective role of COMP‐Ang1 in ischemic rat brain2009 · 35 citations
  4. 4A Human Neutralizing Antibody Specific to Ang‐2 Inhibits Ocular Angiogenesis2011 · 41 citations
  5. 5Renoprotective effect of COMP-angiopoietin-1 in db/db mice with type 2 diabetes2006 · 77 citations