Population
Smooth muscle cells from rat cerebral arteries
Design
Preclinical
Authors
Loading...
No immediate clinical implications; leaves open whether spark-STOC coupling regulates human cerebral vasoregulation.
This preclinical study demonstrates that ryanodine receptors causing Ca2+ sparks are functionally coupled to KCa channels in the surface membrane of cerebral artery smooth muscle cells, providing direct evidence that Ca2+ sparks cause STOCs.
Pérez et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: