Why the study?
Do steroid-eluting electrodes maintain their effect on reducing stimulation thresholds over 10 years compared to non-steroid leads?
Population
20 human patients with implanted unipolar ventricular leads and 25 explanted leads
Comparison
Steroid-eluting unipolar ventricular leads vs Unipolar ventricular leads without steroid
Design
Cohort, double-blind (for the original human study)
Follow-up
10 years
Authors
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May support lead selection favoring steroid-eluting electrodes; extends observational durability data but leaves open randomized confirmation.
Do steroid-eluting electrodes maintain their effect on reducing stimulation thresholds over 10 years compared to non-steroid leads?
Steroid-eluting electrodes maintain low stimulation thresholds and retain sufficient steroid for at least 10 years post-implant.
Mond et al. (1996) studied this question.
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