Why the study?
Does dabigatran compared to rivaroxaban alter the risk of gastrointestinal bleeding in patients requiring anticoagulation?
Population
374 patients on either dabigatran or rivaroxaban from October 2010 to April 2013 across two hospitals
Comparison
Dabigatran vs Rivaroxaban
Design
Cohort
Authors
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Similar GI bleeding rates observed with dabigatran versus rivaroxaban; leaves open differential risk and should not yet alter prescribing.
Does dabigatran compared to rivaroxaban alter the risk of gastrointestinal bleeding in patients requiring anticoagulation?
Dabigatran and rivaroxaban have similar rates of gastrointestinal bleeding, with the highest risk occurring during the first 40 days of therapy for both drugs.
Sherid et al. (2014) studied this question.
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