Why the study?
Does the admittance technique and Wei's equation improve the accuracy of invasive left ventricular volume measurements compared to traditional conductance methods in mice?
Population
Closed-chest mice for echocardiography comparison, additional mice for myocardial permittivity and…
Comparison
Admittance technique (dynamic G) and Wei's… vs Traditional conductance methods (hypertonic…
Design
Preclinical
Authors
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Admittance may refine murine LV volumetry; leaves open translation to clinical invasive hemodynamics.
Does the admittance technique and Wei's equation improve the accuracy of invasive left ventricular volume measurements compared to traditional conductance methods in mice?
The admittance technique and Wei's equation provide more accurate left ventricular volume measurements in mice without the need for hypertonic saline, and are more sensitive to inotropic changes than traditional conductance methods.
Porterfield et al. (2009) studied this question.
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