Why the study?
Does low-dose oral vitamin K supplementation improve anticoagulation control in patients receiving warfarin?
Population
100 participants from 2 RCTs, patients initiating warfarin or already taking a maintenance dose of warfarin…
Comparison
Low-dose oral vitamin K added to warfarin. vs Placebo added to warfarin.
Design
Systematic_review
Authors
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Insufficient evidence precludes routine low-dose vitamin K for warfarin INR control; leaves open benefit in larger RCTs.
Does low-dose oral vitamin K supplementation improve anticoagulation control in patients receiving warfarin?
There is currently insufficient evidence to determine whether low-dose vitamin K supplementation improves INR control in patients with a highly variable response to warfarin.
Mahtani et al. (2014) studied this question.
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