Why the study?
Can NT-proBNP measurement detect right ventricular systolic dysfunction in patients with pulmonary hypertension?
Population
25 patients with pulmonary hypertension
Comparison
NT-proBNP measurement vs Cardiovascular magnetic resonance (CMR) imaging
Design
Cross-sectional
Authors
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May support noninvasive RV dysfunction detection in PH; hypothesis-generating and requires prospective validation before clinical adoption.
Can NT-proBNP measurement detect right ventricular systolic dysfunction in patients with pulmonary hypertension?
An NT-proBNP threshold of >1,685 pg/mL is highly sensitive and specific for detecting right ventricular systolic dysfunction in patients with pulmonary hypertension.
Blyth et al. (2006) studied this question.
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