Why the study?
Does positive end-expiratory pressure (PEEP) alter left ventricular function compared to pulmonary arterial occlusion in anesthetized dogs?
Population
Anesthetized dogs
Comparison
Positive end-expiratory pressure (PEEP) vs Pulmonary arterial occlusion (PAO)
Design
Preclinical
Authors
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Implicates RV stress in PEEP-related LV impairment in this canine model; hypothesis-generating for human ventilatory strategies.
Does positive end-expiratory pressure (PEEP) alter left ventricular function compared to pulmonary arterial occlusion in anesthetized dogs?
Diminished left ventricular function with PEEP is likely due to ventricular interdependence from a stressed right ventricle.
Scharf et al. (1982) studied this question.
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