Why the study?
Does type-1 diabetes with autonomic neuropathy alter brain processing of painful visceral stimuli compared to healthy volunteers?
Population
14 type-1 diabetes patients with autonomic neuropathy and related gastrointestinal symptoms, and 15 healthy…
Comparison
Painful oesophageal electrical stimuli with… vs Healthy volunteers
Design
Case-control
Authors
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Supports altered central visceral processing in diabetic neuropathy; hypothesis-generating and should not yet change practice.
Does type-1 diabetes with autonomic neuropathy alter brain processing of painful visceral stimuli compared to healthy volunteers?
Patients with type-1 diabetes and autonomic neuropathy show evidence of altered central processing and neuronal reorganization in response to visceral stimulation.
Frøkjærl et al. (2010) studied this question.
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