Why the study?
Does the combination of exercise ECG and 201thallium scintigraphy improve risk stratification in patients admitted for but without myocardial infarction compared to either examination alone?
Does the combination of exercise ECG and 201thallium scintigraphy improve risk stratification in patients admitted for but without myocardial infarction compared to either examination alone?
Combining exercise ECG and 201thallium scintigraphy improves risk stratification in patients with suspected but unconfirmed myocardial infarction.
May improve risk stratification in suspected MI without infarction; hypothesis-generating, requires prospective validation before changing practice.
Patients admitted for acute myocardial infarction that is not confirmed (non-AMI) have a prognosis only slightly better than that of patients with confirmed infarction. In a prospective, prognostic study of 158 patients with non-AMI the combination of exercise ECG and transient defects demonstrated at 201thallium scintigraphy identified low- and high-risk groups better than either examination alone. The purpose of a new, still ongoing study of non-AMI patients is to establish a relevant, cost-effective examination programme in order to arrive at a positive diagnosis in each non-AMI patient. Preliminary results of lung perfusion/ventilation scintigraphy suggest a rather low frequency of pulmonary embolism. Preliminary data of oesophageal scintigraphy suggest that about 25% of the non-AMI patients have abnormal mean transit times. The clinical significance of these data are discussed.
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Launbjerg et al. (1990) studied this question.
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