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January 12, 1979Acta Medica Scandinavica

The predictive value of myocardial scintigraphy with 99mtechnetium pyrophosphate in diagnosing acute myocardial infarction

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Why the study?

Does myocardial scintigraphy with 99m technetium-pyrophosphate accurately diagnose or rule out acute myocardial infarction compared to usual procedures?

Population

38 selected patients, consisting of 20 with clinical acute myocardial infarction and 18 without clinical AMI

Comparison

Myocardial scintigraphy with 99m… vs Usual procedures

Design

Cross-sectional

Authors

PHPoul Flemming Høilund‐CarlsenUniversity of Southern DenmarkJBJ BadskjaerFrederiksberg HospitalJHJ. B. HertzUniversity of Copenhagen

Discussion

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Implication

Negative scintigram reliably excludes AMI; leaves open its diagnostic role pending prospective validation.

Structured PICO

Does myocardial scintigraphy with 99m technetium-pyrophosphate accurately diagnose or rule out acute myocardial infarction compared to usual procedures?

P
Population
38 selected patients, consisting of 20 with clinical acute myocardial infarction (AMI) and 18 without clinical AMI
I
Intervention
Myocardial scintigraphy with 99m technetium-pyrophosphate
C
Comparator
Usual procedures (ECG and serum enzyme determination - GO-transaminase and α1-fraction of LDH)
O
Outcome
Predictive value of the method in the detection or disproof of AMIsurrogate

A negative 99m technetium-pyrophosphate myocardial scintigram obtained 2 to 6 days after symptom onset is highly reliable for ruling out acute myocardial infarction.

Cite This Study

Høilund‐Carlsen et al. (1979) studied this question.

synapsesocial.com/papers/6a75efe0f56d87d9178b7529https://doi.org/10.1111/j.0954-6820.1979.tb00699.x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Technetium stannous pyrophosphate myocardial scintigrams in patients with chest pain of varying etiology.1975 · 209 citations
  2. 2Acute subendocardial myocardial infarction in patients. Its detection by Technetium 99-m stannous pyrophosphate myocardial scintigrams.1975 · 139 citations
  3. 3Technetium 99m stannous pyrophosphate myocardial imaging in patients with and without left ventricular aneurysm.1976 · 76 citations
  4. 4Present Status of Positive Scintigraphic Imaging of Myocardial Infarction 1 - Scand. J. clin. Lab. Invest1976 · 1 citations
  5. 5A New Method for Radionuclide Imaging of Acute Myocardial Infarction in Humans1974 · 302 citations